Research Associate, Antibody Analytics, R&D UK Center (Cambridge), Research and Development, Orion Pharma
Orion Pharma
Cambridge, England, United KingdomPosted 13 days agoFull-time
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Research Associate, Antibody Analytics, R&D UK Center (Cambridge), Research and
Development, Orion Pharma
The Antibody Purification and Analytics group is a core part of the newly
established Orion Biologics R&D UK Centre, responsible for supporting the
discovery and development of next-generation biologics, including multispecific
antibodies, antigens, antibody-drug conjugates (ADCs), and CAR-Ts, from early
research through clinical development.
Orion Pharma has recently established a Biologics Research & Development Centre
in the vibrant biomedical ecosystem of Cambridge, UK. The Biologics R&D Centre
represents a central piece in the long-term vision of expansion into biologics
modalities by Orion Pharma. The Centre’s mission is to accelerate the company's
biologics research and development efforts.
The Biologics R&D Centre complements Orion's existing R&D efforts in Finland,
where the company was founded in 19
17. Currently, Orion possesses all of the
functional capabilities necessary for small molecule discovery and development
in Finland. Orion’s expansion into Cambridge, UK marks a pivotal step in
building future innovative biologics treatments, including multi-specific
antibodies, Antibody Drug Conjugates (ADC), and Chimeric Antigen Receptor T
cells (CAR-T).
Independently of geography, Orion Pharma is committed to upholding key Nordic
values. The company has created a culture of straightforward and honest
interactions, and its management emphasizes the balance of professional and home
life, leading to happier and motivated employees. This motivation is key to
meeting the company’s bold mission of becoming a powerhouse of biologics
discovery and development.
We are seeking a highly motivated Antibody Analytics Research Associate to
establish and support Orion Pharma’s characterization platform. This role will
be pivotal in supporting a growing and dynamic pipeline of biologics with a
focus on delivering high-quality material for functional testing, and eventually
clinical development.
• Your responsibilities include the following:
• Execute experiments to assess the quality, stability, and developability of
antibodies and complex biologics, using techniques such as affinity
measurements (SPR), DLS, DSC, DSF, analytical HPLC (SEC-MALS, HIC, etc),
CE-SDS, polyreactivity, AC-SINS, subvisible particle analysis, immunogenicity
and other relevant assays.
• Support the development, optimization, and troubleshooting of analytical
workflows, including sample preparation, instrument operation, and method
execution.
• Maintain accurate and detailed experimental records by documenting assay
conditions and observations in electronic lab notebooks, and ensure
procedures are regularly updated and current.
• Assist with forced degradation studies and other stability profiling
experiments to support early-stage developability assessments.
• Track and analyse experimental data to support interpretation and
decision-making within the Antibody Analytics team.
• Contribute to laboratory maintenance, including calibration of instruments,
inventory management, and ensuring proper operation of analytical equipment.
• Collaborate closely with upstream expression, purification, antibody
discovery and engineering, and functional biology teams to ensure timely and
high-quality data delivery.
• Participate in team meetings and discussions, sharing experimental results
and contributing ideas to improve workflows and problem-solving.
• Comply with all safety and quality standards, following internal SOPs and
maintaining a clean, organized work environment.
This position will report to the Head of Antibody & Protein Analytics Team Lead
within Orion Pharma’s iMeds/R&D organization.
Description of our organization
Orion Pharma’s Innovative Medine’s innovations are within its R&D organization.
The organisation employs top professionals in the field of drug discovery and
development. There are around 400 professionals working in R&D. Orion R&D has
offices in Espoo, Turku and Kuopio in Finland, in Nottingham, UK, and in New
York, NY, USA.
We offer
A unique opportunity for an enthusiastic Antibody Analytics RA to gain
experience characterising novel antibody formats using a broad range of
analytical techniques. The role will help strengthen analytical capabilities at
our new Cambridge, UK location and contribute to the development of a
state-of-the-art antibody discovery powerhouse, with the full support of Orion
Pharma iMeds/R&D.
A highly innovative R&D pipeline and enthusiastic working environment with
possibilities to use your own strengths to advance your competence and career.
The exciting potential to innovate and have an impact on future therapies for
patients.
An excellent working atmosphere based on the appreciation of colleagues,
continuous development, and mutual trust. Learn more about Orion as an employer
https://www.orion.fi/en/careers/orion-as-an-employer/.
Our expectations: A BSc or MSc in Biochemistry, Analytical Chemistry,
Biotechnology, or a related life science discipline, with 1-3 years of practical
laboratory experience gained through industry, academic research, or other
relevant laboratory work.
• Hands-on experience with affinity measurement techniques, including surface
plasmon resonance (SPR) using instruments such as Biacore, or Carterra.
• Hands-on experience with analytical assays used to assess the biophysical
properties of proteins, such as DLS, DSC, DSF, HPLC (SEC, HIC), CE-SDS,
AC-SINS, UV spectrophotometry, and subvisible particle analysis.
• Familiarity with complex biologics such as bispecific or multispecific
antibodies, ADCs, or other novel modalities is advantageous.
• Understanding of basic protein structure-function relationships and how they
influence analytical strategy and molecule developability is desirable.
• Demonstrated ability to follow operating procedures, maintain detailed
laboratory records, and contribute to data reporting and interpretation.
• Strong teamwork and communication skills, with the ability to work
effectively in a collaborative, cross-functional research environment.
• Highly organized, detail-oriented, and committed to maintaining high
standards of lab safety, data integrity, and reproducibility.
#LI-ORION
How to apply and
additional information
We typically review applications already during the application period and may
start interviewing candidates before the application deadline. Therefore, we
invite you to send your application as soon as possible.
Please attach your CV and cover letter by 27 October 2026
Orion Pharma is a globally operating Nordic pharmaceutical company – a builder
of well-being for over a hundred years.
We’re home to more than 4,000 Orionees around the world, and we’re proud to be
known as a responsible employer and a great place to work. At Orion Pharma,
people are truly valued and trusted, encouraged to grow, and supported by a
culture where every voice is heard. We appreciate each other, strive for
excellence, and build the future.
Together we develop, manufacture, and market human and veterinary
pharmaceuticals and active pharmaceutical ingredients. Our extensive portfolio
includes proprietary and generic medicines as well as consumer health products.
The core therapy areas of our pharmaceutical R&D are oncology and pain.
Proprietary products developed by Orion Pharma are used to treat cancer,
neurological diseases, respiratory diseases, and more.
We offer careers with a clear purpose: empowering people to live their lives to
the fullest.
About Orion [https://www.orionpharma.com/about-orion/]